Recombinant Human Interleukin 17A, HIgG1 Fc-tagged, mutant
TypeName: Business Offer
Category:
Offer Date:2019/08/16
Country: United States
Summary: Cat.No.: IL17A-571H Product Overview: The extracellular domain of human IL-17 (AAH67505.1)(Ile20-Ala155) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell. Description: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis
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