anti-HIgG(Fc)-N-DM1 ADC

Creative Biolabs

This ADC product is comprised of an anti-human IgG Fc specific polyclonal antibody conjugated via a noncleavable linker to DM1. The antibody portion is a secondary antibody and the drug portion, DM1, is a cytotoxic small molecule which binds to tubulins, interrupts microtubule dynamics, and induces cell death. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates. https://www.creative-biolabs.com/adc/target-igg-fc-55.htm

anti-HIgG(Fc)-N-DM1 ADC