SMCC-DM1

SMCC-DM1

Creative Biolabs

Linker-Toxin SET, This set is made by DM1 conjugated to SMCC linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells. https://www.creative-biolabs.com/adc/classify-drug-linker-complexes-8.htm

SMCC-DM1