Summary: Cat.No. : GHR-362H Product Overview : Recombinant human GHR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. Description : GHR, also known as growth hormone receptor, is a member of the cytokine receptor family. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, growth hormone acts as an antagonist because of a large difference in affinities at the respective binding sites. This antagonist action can be enhanced further by reducing binding in the low affinity binding site.
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