Summary: Cat.No. : SRC-1358H Product Overview : Recombinant Human SRC(Met 1-Leu 536) fused with His/GST tag at N-terminal was expressed in Insect cells. Description : This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.