Summary: "The vector of anti-TAG-72 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TAG-72. The T cell is genetically modified through transduction with a lentiviral vector expressing scFv of anti-TAG-72 antibody linked to CD28 signaling domains. And the vector product was designed for the treatment of colon cancer. https://www.creative-biolabs.com/car-t/pcdcar1-tag-72-h-28-t-539.htm"