Summary: "The vector of anti-HBV S protein chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human HBV S protein. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-HBV S protein antibody linked to CD8 hinge-transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of cirrhosis, hepatocellular carcinoma (HCC), liver cancer. https://www.creative-biolabs.com/car-t/pcdcar1-hbv-s-protein-h-8%CE%B6-t-534.htm"
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