Summary: "The vector of anti-ROR1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human ROR1. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-ROR1 antibody linked to CD4 transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of B cell-chronic lymphocytic leukemia (B-CLL) and MCL tumor. https://www.creative-biolabs.com/car-t/pcdcar1-ror1-h-4%CE%B6-t-509.htm"
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