Summary: "The vector of anti-CD56 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD56. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD56 antibody linked to CD28 transmembrane domain/ endodomain and CD137 (4-1BB), CD3-zeta signaling domains. And the vector product was designed for the treatment of relapsed refractory myeloma. https://www.creative-biolabs.com/car-t/pcdcar1-cd56-h-28bb%CE%B6-t-465.htm"
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