Summary: "The vector of anti-MUC1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human MUC1. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-MUC1 antibody linked to CD28 transmembrane domain/ endodomain and OX40, CD3-zeta signaling domains. And the vector product was designed for the treatment of MUC1-expressing tumors . https://www.creative-biolabs.com/car-t/pcdcar1-muc1-h-28ox%CE%B6-t-454.htm"
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