Recombinant Human Fibroblast Growth Factor 18, HIgG1 Fc-tagged
TypeName: Business Offer
Category:
Offer Date:2019/08/16
Country: United States
Summary: Cat.No.: FGF18-224H Product Overview: The extracellular domain of human FGF-18(AAH06245.1)(Glu28-Ala207) is fused to the N-terminus of the Fc region of a human IgG1was expressed in CHO cell. Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures