Summary: Cat.No.: APP-586H Product Overview: Recombinant Human APP (Met 1-Leu 669) (NP_958816.1), fused with the C-terminal Fc region of human IgG1, was produced in Human Cell. Source: Human Cells Species: Human Tag: Fc Form: Lyophilized from sterile PBS, pH 7.4 Molecular Mass: The recombinant human APP/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 890 amino acids and predicts a molecular mass of 101 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhAPP/Fc monomer is approximately 150-160 kDa due to the glycosylation.
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