Summary: Creative Biolabs provides GLP-compliant in vivo test services for anti-PSMA CAR-T cell therapy in prostate cancer. PSMA (prostate-specific membrane antigen), well known as FOLH1 (folate hydrolase 1) or GCP II (glutamate carboxypeptidase II), encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. As a zinc metalloenzyme, PSMA residing in membrane catalyzes the hydrolysis of N-acetylaspartylglutamate (NAAG) to glutamate and N-acetylaspartate (NAA), also other alternative substrates like nutrient folate.
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