Summary: Creative Biolabs provides GLP-compliant in vivo test services for anti-MAGEA3 CAR-T cell therapy in multiple human malignancies: melanoma, thyroid cancer, pancreatic cancer, gastric cancer, etc. MAGEA3 (melanoma-associated antigen 3) is a member of melanoma-associated antigen family, and has a conserved MAGE homology domain (MHD: 116 aa – 286 aa). Notwithstanding the restricted expression only in immune privileged reproductive tissues (for instance, primary spermatocytes, spermatogonia and placental trophoblast), the normal function of MAGEA3 in healthy cells remains to be discovered.
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