Summary: The basis of manufacturing biologically active products relies on generating high quality cell lines which comply with current regulatory guidelines. However, the construction of a validated cell line requires sophisticated and time-consuming work. Scientists from Creative Biolabs use Glutamine Synthetase (GS) or Dihydrofolate Reductase (DHFR) systems to construct the stable cell lines. https://www.creative-biolabs.com/Manufacturing-Cell-Line-Development.html