Knobs-into-holes

TypeName: Business Offer
Category:
Offer Date:2019/05/25
Country: United States
Summary: Scientists from Creative Biolabs introduced knobs-into-holes amino acid changes to perform rational design in antibody engineering. The principle is that heavy chains (H) of human immunoglobulin IgG interact at the level of their CH3 domains directly, whereas, at the level of their CH2 domains, they interact via the carbohydrate attached to the Asn N84.4 in the DE turn. https://www.creative-biolabs.com/KNODBS-INTO-HOLE.html
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OfferId: 4455
Name:Creative Biolabs
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