Anti-cKIT (20376)-SMCC-DM1 ADC

TypeName: Business Offer
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Offer Date:2017/09/28
Country: United States
Summary: This ADC product is comprised of an anti-cKIT monoclonal antibody (20376) conjugated via a SMCC linker to DM1. The DM1 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. http://www.creative-biolabs.com/adc/target-ckit-23.htm
Description:
OfferId: 403
Name:Creative Biolabs
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