Summary: This ADC product is comprised of an anti-CEACAM5 monoclonal antibody conjugated via a Phy-lys linker to SN-38. The SN-38 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage. http://www.creative-biolabs.com/adc/target-ceacam5-21.htm