Summary: This ADC product is comprised of an anti-TNFRSF17 monoclonal antibody (clone CA8) conjugated via a VC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tnfrsf17-98.htm
Description: This ADC product is comprised of an anti-TNFRSF17 monoclonal antibody (clone CA8) conjugated via a VC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tnfrsf17-98.htm
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