Summary: This ADC product is comprised of an anti-TNFRSF17 monoclonal antibody (clone 1E1) conjugated via a SMCC linker to DM1. The DM1 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tnfrsf17-98.htm
Description: This ADC product is comprised of an anti-TNFRSF17 monoclonal antibody (clone 1E1) conjugated via a SMCC linker to DM1. The DM1 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tnfrsf17-98.htm
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