Summary: This ADC product is comprised of an anti-TNFRSF17 monoclonal antibody (clone 2A1) conjugated via a PEG4-Mal linker to DM4. The DM4 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM4 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tnfrsf17-98.htm
Description: This ADC product is comprised of an anti-TNFRSF17 monoclonal antibody (clone 2A1) conjugated via a PEG4-Mal linker to DM4. The DM4 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM4 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tnfrsf17-98.htm
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