Summary: This ADC product is comprised of an anti-TMEFF2 monoclonal antibody conjugated via a Mc-VC-PABC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tmeff2-96.htm
Description: This ADC product is comprised of an anti-TMEFF2 monoclonal antibody conjugated via a Mc-VC-PABC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-tmeff2-96.htm