Summary: This ADC product is comprised of an anti-TACSTD2 monoclonal antibody (hRS7) conjugated via a CL2E linker to SN-38 . The SN-38 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage. https://www.creative-biolabs.com/adc/target-tacstd2-93.htm
Description: This ADC product is comprised of an anti-TACSTD2 monoclonal antibody (hRS7) conjugated via a CL2E linker to SN-38 . The SN-38 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage. https://www.creative-biolabs.com/adc/target-tacstd2-93.htm