Summary: This ADC product is comprised of an anti-CD33 monoclonal antibody (cloneh2H12d) conjugated via a linker to SGD-1910. The SGD-1910 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, calicheamicin binds to DNA, causes DNA damage, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-cd33-11.htm
Agriculture & Food
Business Services
Electronics, IT and Telecoms
Leisure & Tourism
Minerals
Textiles, Clothing, Leather,
Transport & Logistics
