Summary: As many of the cytotoxic drugs conjugated to a monoclonal antibody to form an antibody-drug conjugate (ADC) are highly hydrophobic, this covalent chemical conjugation has been shown to exert a significant effect on ADC’s physical stability, a factor that is of crucial importance for downstream ADC development. Scientists from Creative Biolabs adopt a comprehensive set of analytical approaches to fully evaluate ADC physical stability to facilitate the design and improvement of ADCs. Scientists from Creative Biolabs provide comprehensive analytical approaches to evaluate the physical stability of an antibody-drug conjugate. https://www.creative-biolabs.com/adc/adc-physical-stability-analysis.htm
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