UV Photo-crosslinking

TypeName: Business Offer
Category:
Offer Date:2018/08/23
Country: United States
Summary: Creative Biolabs now offers an innovative strategy for antibody-drug conjugate (ADC) preparation using UV photo-crosslinking. This strategy includes two approaches: (1) UV triggered conjugation onto antibody nucleotide binding sites (NBS) and (2) conjugation via photoactive protein Z. UV-NBS conjugation utilizes UV-energy to initiate a photo-crosslinking reaction between the NBS and the NBS-ligand to achieve controlled site-specific drug to antibody conjugation while the protein Z strategy couples a cytotoxic drug to a photoactive protein Z and then specifically attaches the complex to the Fc region of an antibody upon the exposure to long wavelength UV, generating homogeneous ADCs. Taking advantage of the unique antibody nucleotide binding sites, Creative Biolabs provides an innovative ADC development strategy using UV photo-crosslinking to generate ADCs for various applications https://www.creative-biolabs.com/adc/uv-photo-crosslinking.htm
Description: [RequestDescription]
OfferId: 1993
Name:Creative Biolabs
Telphone:
Categories