Summary: https://www.creative-biolabs.com/car-t/pcdcar1-egp-2-h-ζ-t-255.htm The vector of anti-EGP-2 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human EGP-2. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGP-2 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of EGP-2+ colon cancer.
Description: https://www.creative-biolabs.com/car-t/pcdcar1-egp-2-h-ζ-t-255.htm The vector of anti-EGP-2 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human EGP-2. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGP-2 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of EGP-2+ colon cancer.