Summary: https://www.creative-biolabs.com/car-t/pcdcar1-tag-72-h-28bbζ-t-549.htm The vector of anti-TAG-72 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TAG-72. The T cell is genetically modified through transduction with a lentiviral vector expressing scFv of anti-TAG-72 antibody linked to CD28 transmembrane domain/ endodomain and CD137 (4-1BB), CD3-zeta signaling domains. And the vector product was designed for the treatment of colon cancer.
Description: https://www.creative-biolabs.com/car-t/pcdcar1-tag-72-h-28bbζ-t-549.htm The vector of anti-TAG-72 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TAG-72. The T cell is genetically modified through transduction with a lentiviral vector expressing scFv of anti-TAG-72 antibody linked to CD28 transmembrane domain/ endodomain and CD137 (4-1BB), CD3-zeta signaling domains. And the vector product was designed for the treatment of colon cancer.
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