Summary: https://www.creative-biolabs.com/car-t/pcdcar1-tag-72-h-b2cζ-t-548.htm The vector of anti-TAG-72 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TAG-72. The T cell is genetically modified through transduction with a lentiviral vector expressing scFv of TAG-72 antibody linked to b2c and CD3-zeta signaling domains. And the vector product was designed for the treatment of colon cancer.
Description: https://www.creative-biolabs.com/car-t/pcdcar1-tag-72-h-b2cζ-t-548.htm The vector of anti-TAG-72 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TAG-72. The T cell is genetically modified through transduction with a lentiviral vector expressing scFv of TAG-72 antibody linked to b2c and CD3-zeta signaling domains. And the vector product was designed for the treatment of colon cancer.