Summary: https://www.creative-biolabs.com/car-t/pcdcar1-cd56-h-8ζ-t-462.htm The vector of anti-CD56 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD56. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD56 antibody linked to CD8 hinge-transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of relapsed refractory myeloma.
Description: https://www.creative-biolabs.com/car-t/pcdcar1-cd56-h-8ζ-t-462.htm The vector of anti-CD56 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD56. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD56 antibody linked to CD8 hinge-transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of relapsed refractory myeloma.
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