Summary: "The vector of anti-CD37 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD37. The T cells are genetically modified through transduction with a vector expressing scFv of anti-CD37 antibody linked to a CD28 transmembrane domain/ endodomain and OX40, CD3-zeta signaling domains. And the vector product was designed for the treatment of B cell malignancies, such as chronic lymphocytic leukemia (CLL), B cell non-Hodgkin lymphoma (B cell NHL), hairy cell leukemia (HCL), acute lymphoblastic leukemia (ALL) and lymphoplasmacytic lymphoma. https://www.creative-biolabs.com/car-t/pcdcar1-cd37-h-28ox%CE%B6-t-144.htm"
Description: "The vector of anti-CD37 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD37. The T cells are genetically modified through transduction with a vector expressing scFv of anti-CD37 antibody linked to a CD28 transmembrane domain/ endodomain and OX40, CD3-zeta signaling domains. And the vector product was designed for the treatment of B cell malignancies, such as chronic lymphocytic leukemia (CLL), B cell non-Hodgkin lymphoma (B cell NHL), hairy cell leukemia (HCL), acute lymphoblastic leukemia (ALL) and lymphoplasmacytic lymphoma. https://www.creative-biolabs.com/car-t/pcdcar1-cd37-h-28ox%CE%B6-t-144.htm"
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