Summary: "The vector of anti-CD276 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD276. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD276 antibody linked to a CD28 transmembrane domain/ endodomain and CD3-zeta signaling domains. And the vector product was designed for detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed, for example, chronic lymphocytic leukemia (CLL). https://www.creative-biolabs.com/car-t/pcdcar1-cd276-h-28%CE%B6-t-113.htm"
Description: "The vector of anti-CD276 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD276. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD276 antibody linked to a CD28 transmembrane domain/ endodomain and CD3-zeta signaling domains. And the vector product was designed for detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed, for example, chronic lymphocytic leukemia (CLL). https://www.creative-biolabs.com/car-t/pcdcar1-cd276-h-28%CE%B6-t-113.htm"
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